Activity guided isolation and modification of juglone from Juglans regia as potent cytotoxic agent against lung cancer cell lines

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Activity guided isolation and modification of juglone from Juglans regia as potent cytotoxic agent against lung cancer cell lines

BACKGROUND Juglans regia has been found to exhibit significant anticancer activity against various human cancer cell lines. This study was undertaken to isolate the active chemical constituent (Juglone) and to investigate its cytotoxic activity along with its various analogs against different human cancer cell lines. METHODS Isolation of juglone, a napthoquinone, from the chloroform extract o...

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Comparison of cytotoxic activity of some Iranian Stachys spp. extracts on different cancer cell lines

The genus Stachys belongs to Lamiaceae family with about 300 species and worldwide distribution. In the present study, the cytotoxic activity of four fractions of different Satchys species (S. byzatina C. Koch., S. inflata Benth., S. setifera Ten. and S. persica Gmel.), has been investigated against HT-29 (colon carcinoma), Caco-2 (colorecta...

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Cytotoxic Activity of Juniperus excelsa M. Bieb. Leaves Essential Oil in Breast Cancer Cell Lines

Background and objectives: Juniperus excelsa is a flowering plant that has been applied as traditional medicine for treatment of various disorders such as dysmenorrhea, bronchitis and colds, jaundice and tuberculosis. The aims of the present study were analyzing J. excelsa essential oil and investigation of its cytotoxic activity on three breast cancer cell li...

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Antihemolytic activity and mineral contents of Juglans regia L. flowers.

OBJECTIVES Juglans (J.) regia L. is known to possess many biological properties. In this study, antihemolytic activity of methanol extract of Juglans regia L. flower were investigated. MATERIALS AND METHODS Antihemolytic activities of Juglans regia L. flowers were evaluated by various in vitro assays. In addition, scavenging of hydrogen peroxide and mineral contents of flowers were determined...

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ژورنال

عنوان ژورنال: BMC Complementary and Alternative Medicine

سال: 2015

ISSN: 1472-6882

DOI: 10.1186/s12906-015-0920-0